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The longer it remains exposed, the greater the risk that it will lose effectiveness

Sperm cryopreservation and DNA methylation: possible implications for ART success and the health of offspring

The high response rate to treatment with IBAT (odevixibat) in these patients suggests that in PFIC4, despite tight junction dysfunction, there is a regular passage of BAs from the hepatocytes to the biliary tree and the bowel, allowing odevixibat to interrupt the enterohepatic circulation and decrease the recirculating BA pool [1, 42, 47]

(2016) suggests that the antioxidant astaxanthin can ameliorate behavioral deficits in SZ mice

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